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KMID : 0358319930340030468
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Korean Journal of Urology
1993 Volume.34 No. 3 p.468 ~ p.475
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Testis Tumor: A Clinical Experience of 20 Years
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Abstract
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Forty-six patients with testicular tumor were treated at our hospital from 1971 to 1990. There were 25 children(13 yolk sac tumors, 10 teratomas, 1 teratocarcinoma and 1 acute lymphocytic leukemia) and 21 adults(11 seminomas, 4 non-seminomatous
germ
cell tumors and 6 non-germ cell tumors). Testicular tumors with clinical evidence of cryptorchidism were 4 seminomas and 2 non seminomas. Serum AFP of HCG were observed in 3 patients of 8 seminomas, 1 of 5 teratomas, 7 of 9 yolk sac tumors and 4
of
5
non-seminomatous germ cell tumors(NSGCT). Four stage I seminomas and 1 NSGCT were tumor free of 2 years after radical orchiectomy and 2 of 4 seminomas were received prophylactic radiotherapy. Two stage II seminomas and 1 NSGCT treated with PVB
regimen
and radiotherapy were tumor free of 2 years but stage III seminomas and NSGCT died during chemotherapy. All stage I yolk sac tumors and teratomas were tumor free of 2 years by surveillance only following radical orchiectomy but stage II and III
yolk sac
tumors died during chemotherapy. We have suggested that poor result of stage III testicular tumors can be attributed to few cases with more aggressive and more toxic chemotherapy in the unfavorable prognosis disease (advanced extent) and poor
compliance
of patient of therapy.
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